Sperm Damage: Bisphenol A Exposure Causes Sperm DNA to Fragment

We're not trying to stack up the evidence against Bisphenol A; BPA is doing that just fine without our help. Research from the University of Cincinnati presented at the 67th annual meeting of the American Society for Reproductive Medicine demonstrates that BPA exposure in vitro increases sperm fragmentation, manifesting as double-strand breaks. While the researchers' sample size was small, the findings which were presented on Monday, October 17th at the annual meeting of the American Society for Reproductive Medicine are significant. Much like the way estradiol damages sperm, the estrogenic nature of BPA causes the same type of damage.

IVFConnections.com is encouraged that researchers are continuing to look into BPA and its effects on human reproduction, because while its use has declined slightly in recent years, about 93% of people in the U.S. have measurable levels of BPA in their urine. This is an issue that will not go away until the evidence is overwhelming -- so let's step up the research ASAP.


O-17 BPA Confers Direct Genotoxicity to Sperm with Increased Sperm DNA Fragmentation
D.H. Wu, Y.-K. Leung, M.A. Thomas, R. Maxwell, S.-M. Ho.